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Regorafenib Renews Hope in Hepatocellular Carcinoma

OncLive - Nov 14, 2016
After numerous failed attempts to uncover an effective second-line systemic therapy for patients with hepatocellular carcinoma (HCC) who progressed on sorafenib, optimism was fading in the industry; however, that all changed with regorafenib (Stivarga ...

Combination therapy effectively treats hepatocellular carcinoma in mice [PreClinical]

2 Minute Medicine - Nov 17, 2016
1. When combined with hepatic artery ligation, the current treatment for hepatocellular carcinoma (HCC), tirapazimine (TPZ) was found to decrease tumor recurrence in mice. 2. TPZ and hepatic artery ligation together led to almost complete necrosis of ...

Lrig1 is a positive prognostic marker in hepatocellular carcinoma

Dove Medical Press - Nov 16, 2016
Background: The prevalence of hepatocellular carcinoma (HCC) is increasing worldwide. As a consequence, there is an urgent need for identifying molecular markers of HCC development and progression. Recently, several studies have suggested that the ...

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Hepatocellular Carcinoma books

Multidisciplinary Treatment of Hepatocellular Carcinoma

It is now widely accepted that multidisciplinary collaboration and multimodality treatment approaches are important in improving the survival of patients with hepatocellular carcinoma. In this comprehensive textbook, internationally renowned experts in the field present and discuss the various strategies employed in the treatment of the disease. Up-to-date information is provided on the indications for and outcome of a range of treatment options, including surgical resection, liver transplantation, radiofrequency ablation, transarterial chemoembolization, yttrium-90 transarterial radioembolization, and systemic therapy.
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Hepatocellular Carcinoma: Diagnosis and Treatment

• Hepatocellular carcinoma (HCC) used to be regarded as a rare disease. However, the increasing numbers of chronic HCC carriers in the U.S. and subsequent increased incidences of HCC seen in most large medical centers means that it is no longer an uncommon disease for gastroenterologists or oncologists to encounter and its incidence and epidemiology are changing. During this exciting time in the field of HCC basic science and clinical management, many changes are simultaneously occurring at multiple levels of our understanding and management of the disease.
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Hepatocellular Carcinoma: Cellular and Molecular Mechanisms and Novel Therapeutic Strategies

by: Rajagopal N. Aravalli, Clifford J. Steer

This book provides up-to-date information on the development and progression of hepatocellular carcinoma (HCC) with a review of the cellular and molecular mechanisms involved in the disease process. Recent research in HCC has led to significant progress in our understanding of the cellular processes and molecular mechanisms that occur during multi-stage events that lead to hepatocarcinogenesis. The emergence of micro RNAs and molecular targeted therapies have added a new dimension in our efforts to combat this deadly disease, Chapters include discussion and evaluation of current intervention strategies and therapeutic options and a focus on the novel approaches that are being pursued, such as micro-RNA based therapies and personalized medicine to treat liver cancer.
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Pathology of Hepatocellular Carcinoma

by: Masamichi Kojiro
This book covers the huge advances made in clinical diagnosis enabling earlier detection, while addressing the recent progress made in treatment of hepatocellular carcinoma (HCC) to enable successful therapy.

It draws on the expertise of an internationally recognized author famed for his understanding, knowledge and efforts in defining terms and diagnosis in this area.

The text reviews the full range of pathological information of HCC based on the study of surgical cases and biopsy materials, along with images, to help compare findings that may be encountered by pathologists.
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Hepatocellular Carcinoma: Optimal Treatment and Transplantation

Monday, February 3, 2014 Presented by Gabriel T. Schnickel, MD About the Henry Ford Transplant Institute Lecture Series The Henry Ford Transplant Institute is ...


hepatocellular carcinoma icd 9 hepatocellular carcinoma staging hepatocellular carcinoma prognosis hepatocellular carcinoma symptoms hepatocellular ...


In this mini lecture, Dr. Gish discusses three different liver complications; Liver Cancer, Hepatocellular Carinoma, and Hepatoma. Hepatocellular carcinoma is ...

Update in the Clinical Management of Hepatocellular Carcinoma

A Department of Medicine Grand Rounds presented by Augusto Villanueva, MD, PhD, Assistant Professor of Medicine (Liver Diseases).